Lamixon^®

Lamixon® reduces neuronal excitability through multiple mechanisms, including modulation of neuronal signal conduction and neurotransmitter activity. As a result, it helps reduce the frequency and severity of seizures while also contributing to mood stabilization in affected patients.

• Epilepsy (Partial and Generalized Seizures)
• Bipolar Disorder

Scored 25 mg, 50 mg, and 100 mg Tablets

• Take Lamixon® exactly as prescribed by your physician. If you are uncertain about the proper use of this medication, consult your physician or pharmacist.
• To achieve the best therapeutic outcome, do not alter the dose or duration of treatment without medical advice.
• Lamixon® may be taken with or without food.
• Do not chew or crush the tablets.

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time or an additional dose to make up for a missed dose.

If more than the prescribed dose is taken, contact your physician immediately or seek emergency medical attention.

Before and during treatment, your physician may periodically monitor the following:

• Signs and symptoms of severe hypersensitivity reactions
• Complete blood cell count (CBC) and related clinical manifestations (e.g., fever, sore throat, oral ulcers, infections, bruising)
• Serum concentrations of concomitantly administered antiepileptic medications
• Liver and kidney function tests
• Electrocardiogram (ECG)
• Changes in disease symptoms and the emergence or worsening of suicidal ideation in patients with bipolar disorder
• Signs and symptoms of aseptic meningitis (severe headache, photophobia, neck stiffness, and fever)

• Hypersensitivity to lamotrigine or any component of the formulation

Symptoms of hypersensitivity may include:

• Skin rash
• Mucosal lesions
• Urticaria
• Severe itching
• Swelling of the lips, tongue, or throat
• Shortness of breath

• Abrupt discontinuation or rapid dose reduction of lamotrigine may result in serious adverse effects and recurrent seizures. Therefore, treatment should be discontinued gradually under close medical supervision.
• When lamotrigine is used for bipolar disorder, consult your physician immediately if symptoms worsen or suicidal thoughts develop.
• Seek immediate medical attention if severe hypersensitivity reactions occur, including widespread rash, redness, swelling, blistering, skin peeling, eye redness, or sores in the mouth, throat, nose, or eyes.
• Concomitant use of certain medications may increase the risk of serious adverse reactions. Inform your physician of all medications you are currently taking to avoid potential drug interactions.
• Inform your physician if you have heart disease, liver disease, kidney impairment, or a history of bariatric surgery.
• Lamotrigine may cause drowsiness or dizziness. Avoid driving, operating heavy machinery, or engaging in activities requiring full mental alertness until you know how the medication affects you.

If treatment with lamotrigine is required during pregnancy or breastfeeding, consult your physician.

The use of lamotrigine during pregnancy and lactation should be based on specialist medical advice, taking into consideration both the potential benefits and risks of therapy.

Like all medicines, Lamixon® may cause side effects, although not everybody experiences them. Possible adverse reactions include:

• Headache, dizziness, diplopia, blurred vision
• Balance disturbances (gait abnormalities, impaired coordination)
• Sleep disturbances (insomnia or somnolence)
• Nausea, vomiting, diarrhea, dyspepsia, constipation, decreased appetite
• Tremor, depression, anxiety, irritability, speech disturbances, impaired concentration
• Runny nose, throat irritation, cough
• Skin rash, itching
• Painful menstruation, genital infections, amenorrhea

Consult your physician or pharmacist before taking lamotrigine concomitantly with any other medications or dietary supplements.

Each package contains 30 tablets (3 blisters of 10 tablets each).

• Store below 30°C, protected from light and moisture.
• The product may be used until the last day of the month indicated as the expiration date on the package.
• Do not use or store expired medicines.
• Keep out of the reach of children.
• Do not remove the tablets from their original packaging until ready for use.

1. Lamotrigine: Drug Information, UpToDate, 2025.
2. Electronic Medicines Compendium (SmPC)
3. Lamotrigine Prescribing Information (FDA)