Ompicare^®

Ompicare® belongs to a group of medicines called proton pump inhibitors, which reduce stomach acid secretion.

• Return of stomach acid to the esophagus, or reflux (GERD)
• Dyspepsia and heartburn
• Treatment of esophagitis
• Prevention and treatment of ulcers in the stomach and upper intestine (duodenum)
• Treatment regimen for Helicobacter pylori infection
• Prevention of ulcers caused by nonsteroidal anti-inflammatory drugs (such as Naproxen and Mefenamic acid)
• Prevention of excessive stomach acid secretion caused by pancreatic or duodenal tumors (Zollinger–Ellison syndrome)
• Prevention of aspiration (airway obstruction caused by entry of foreign material during anesthesia

20 mg enteric-coated capsule.

Take Ompicare® exactly as directed by your physician. If you are unsure about the correct way to take the medicine, consult your physician or pharmacist.

Take Ompicare® 30 to 60 minutes before food, preferably before breakfast. If twice-daily use is needed, take it before breakfast and dinner.

Swallow Ompicare® whole. Do not chew, crush, or split it. If the capsule is opened, swallow the granules inside and avoid crushing the granules.

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Avoid taking two doses at the same time or taking an extra dose.

If you take more than the recommended amount, inform your physician immediately or go to a medical center.

• Helicobacter pylori test
• Blood magnesium level
• Bone density and fractures during long-term use
• Diarrhea caused by Clostridioides difficile infection
• Signs of lupus

• History of hypersensitivity to Omeprazole or any component of the formulation
• History of hypersensitivity to other proton pump inhibitors (Pantoprazole, Lansoprazole, Rabeprazole, or Esomeprazole)

• During Omeprazole treatment, the use of some medicines may lead to serious adverse effects. Inform your physician about all medicines you are taking to help prevent drug interactions and unwanted effects.
• Even if you feel better, continue taking Omeprazole until the end of the treatment course as directed by your physician.
• Omeprazole requires dose adjustment in patients with severe liver impairment. Inform your physician if you have this condition.
• Omeprazole may reduce the therapeutic effects of clopidogrel. Inform your physician if you are taking clopidogrel.
• Omeprazole may affect the results of some laboratory tests. Inform your physician that you are taking this medicine before testing.
• Long-term use of Omeprazole may reduce vitamin B12 absorption. If symptoms of vitamin B12 deficiency occur, such as muscle weakness, fatigue, paleness, mood changes, or tingling in the limbs, vitamin B12 supplementation may be used after consulting your physician.
• Inform your physician immediately if you have unexplained weight loss, difficulty swallowing, stomach pain or indigestion, vomiting or bloody vomiting, black or bloody stool, or severe or persistent diarrhea.
• If severe hypersensitivity symptoms occur — such as redness, swelling, skin rash, blisters, hives, itching, wheezing, tightness in the chest or throat, difficulty breathing, swallowing, or speaking, unusual hoarseness, or swelling of the mouth, face, lips, tongue, or throat — seek medical care immediately.
• Omeprazole may increase the risk of diarrhea caused by Clostridioides difficile. Inform your physician immediately if you have symptoms such as stomach pain, very loose or watery stool, or bloody stool.
• Long-term treatment (more than one year) with Omeprazole is not recommended for children.
• Avoid long-term self-directed use of Omeprazole without consulting your physician.

Consult your physician or pharmacist before using Omeprazole during pregnancy or breastfeeding.

Like all medicines, Omeprazole may cause unwanted side effects along with its desired therapeutic effects, although not everyone experiences them. Possible side effects include:

• Headache
• Hypersensitivity or skin rash
• Joint pain
• Abdominal pain, diarrhea, nausea, bloating, vomiting, reflux, and constipation
• Upper respiratory tract infection and cough

Consult your physician or pharmacist about using Omeprazole together with other medicines or supplements.

Each bottle contains 28 capsules.

• Store below 30°C, protected from light and moisture.
• The medicine may be used until the end of the month stated in the expiry date on the package. Do not use or store expired medicines.
• Keep the medicine out of the reach of children.
• Do not remove the medicine from its original packaging before use.

1. Omeprazole: Drug information, UpToDate 2025
2. Medicines.org.uk product information for Omeprazole.