Lazaro^®

Generic name: Losartan Potassium

Dosage form: Film-coated tablets 25 mg and 50 mg

Drug class: Antihypertensive

Indication: This medication is used to control blood pressure in patients with hypertension.

Lazaro^®

Lazaro^® (Losartan) blocks the angiotensin II receptor, causing vasodilation and lowering blood pressure.

Indications for Lazaro^®

• Treatment of chronic hypertension in adults and children ≥6 years
• Proteinuric chronic kidney disease
• Heart failure
• Acute coronary syndrome
• Post-transplant erythrocytosis
• Myocardial infarction
• Chronic proteinuria in non-diabetic patients
• Marfan syndrome with aortic aneurysm

Dosage Form

• Film-coated tablet 25 mg
• Film-coated, scored tablet 50 mg

How to use and dosage

Take exactly as prescribed and do not discontinue treatment without medical advice. Treatment requires close medical supervision at initiation, during therapy, and when discontinuing.

Swallow with a glass of water, with or without food, preferably at the same time each day.

Missed dose

Take as soon as you remember. If it is near the time of the next dose, skip the missed dose. Do not take a double dose.

Overdose

If you take more than prescribed, contact your doctor immediately.

Monitoring during treatment

• Blood pressure
• Serum electrolytes (e.g., potassium—especially if using potassium-sparing diuretics, potassium supplements, or potassium salts)
• Serum creatinine and urea

Contraindications

• Hypersensitivity to Losartan or any component of the formulation
• Concomitant use with Aliskiren in patients with diabetes or moderate-to-severe renal impairment
• Ascites due to cirrhosis or treatment-resistant ascites
• Pregnancy

Warnings and precautions

• Patients with a history of angioedema (swelling of face, lips, throat, or tongue) should be monitored.
• Symptomatic hypotension may occur in volume- or salt-depleted patients (e.g., on high-dose diuretics); correct volume status before starting.
• Use with caution in aortic or mitral valve stenosis, or hepatic or renal impairment.

Use in pregnancy and breastfeeding

Contraindicated during pregnancy and breastfeeding.

Possible side effects

As with any medicine, side effects may occur (not everyone gets them), including:

• Acute kidney injury
• Hyperkalemia (high potassium)
• Dizziness, fatigue, or weakness
• Skin rash
• Diarrhea, abdominal pain, nausea, or vomiting
• Cough

Drug interactions

Consult your doctor or pharmacist before using Lazaro^® with other medicines or supplements.

Packaging

Each pack contains 30 tablets (3 blisters × 10 tablets).

Storage

• Store below 30°C, away from light and moisture.
• Use until the end of the expiry month printed on the pack.
• Keep out of the sight and reach of children.
• Do not remove from original package until use.

Sources

1. Losartan: Drug Information, UpToDate 2025
2. http://www.medicines.org.uk/emc/product/7800/spmc