Berwin^®

Berwin®

Generic name: Buspirone Hydrochloride
Dosage form: 5 mg and 10 mg tablets
Drug class: Antianxiety Agent
Indication: This medication is mainly used for the treatment of anxiety.

Berwin®

Berwin® (Buspirone Hydrochloride) is an anxiolytic medication that exerts its clinical effects by binding to serotonin and dopamine receptors.

Indications for Berwin®

• Anxiety Disorders 
• Adjunctive treatment of unipolar depression

Dosage Forms of Berwin®

• Oral tablets: 5 mg and 10 mg

How to Use and Dosage of Berwin®

• Take Berwin® exactly as prescribed by your doctor, and always take it either consistently with food or on an empty stomach.
• Do not stop taking the medication—even if you feel better—without consulting your physician.
• Avoid consuming large amounts of grapefruit juice during treatment.

Missed Dose of Berwin®

If you forget a dose, take it as soon as you remember.
If it is close to the time of your next dose, skip the missed dose.
Do not take two doses at the same time or take an extra dose.

Overdose of Berwin®

If you take more than the prescribed amount, notify your doctor immediately or go to a medical center.

Monitoring Requirements During Treatment With Buspirone Hydrochloride

• Patient’s mental and motor status
• Excessive increase in heart rate, blood pressure, or body temperature
• Gastrointestinal symptoms such as nausea, vomiting, and diarrhea
• Seizures

Contraindications for Buspirone Hydrochloride

• History of hypersensitivity to buspirone or any component of the formulation
• Concomitant use with monoamine oxidase inhibitors (MAOIs) (e.g., moclobemide, selegiline, tranylcypromine) or within 14 days before or after taking buspirone
• Concomitant use with reversible MAO inhibitors
• Severe hepatic or renal impairment

Warnings and Precautions for Buspirone Hydrochloride

If you experience symptoms such as increased body temperature, irritability, tremor, muscle stiffness, or flushing, consult your doctor immediately.

• Buspirone may cause drowsiness or dizziness; if this occurs, avoid driving or operating heavy machinery.
• If you develop abnormal body movements, twitches, imbalance, or difficulty swallowing or speaking, notify your doctor.
• Use buspirone with caution in patients with hepatic or renal impairment, or those who have undergone bariatric surgery. Inform your physician if you have any of these conditions.

Use of Buspirone Hydrochloride During Pregnancy and Breastfeeding

Limited information is available regarding the use of buspirone hydrochloride during pregnancy and breastfeeding. Therefore, its use during pregnancy is not recommended, and alternative medications are preferred unless the potential benefits outweigh the risks.

Use of buspirone hydrochloride during breastfeeding is not recommended.

Side Effects of Buspirone Hydrochloride

Not everyone experiences side effects. Possible adverse effects include:

• Dizziness or drowsiness
• Irritability
• Headache
• Gastrointestinal problems

Drug Interactions with Buspirone Hydrochloride

Consult your doctor or pharmacist before using buspirone hydrochloride with any other medications or supplements.

Packaging of  Berwin®

Each package contains 30 tablets (3 blister packs of 10 tablets each).

Storage Conditions for Berwin®

• Store below 30°C, away from light and moisture.
• The medication can be used until the end of the month indicated on the expiration date. Do not use outdated medication.
• Keep out of reach of children.
• Do not remove tablets from the original packaging until use.

References

1. Buspirone: Drug Information, UpToDate 2025
2. electronic Medicines Compendium (eMC)