Antimicrobial

Ciprox200®(Ciprofloxacin)


Ciprox200®(Ciprofloxacin)

CIPROX (ciprofloxacin hydrochloride) lyophilized powder and CIPRO (ciprofloxacin) Oral Suspension are synthetic antimicrobial agents for oral administration. Ciprofloxacin hydrochloride, USP, a fluoroquinolone, is the monohydrochloride monohydrate salt of 1-cyclopropyl-6-fluoro-1, 4-dihydro-4-oxo-7-(1-piperazin yl)-3quinolinecarboxylic acid. It is a faintly yellowish to light yellow crystalline substance with a molecular weight of 385.8. Its empirical formula is C17H18FN3O3•HCl•H2O and its chemical structure is as follows:
CIPROX® (ciprofloxacin hydrochloride) Structural Formula Illustration
Ciprofloxacin is 1-cyclopropyl-6-fluoro-1,4-dih ydro-4-oxo-7-(1-piperazinyl)- 3-quinolinecarboxylic acid. Its empirical formula is C17H18FN3O3 and its molecular weight is 331.4. It is a faintly yellowish to light yellow crystalline substance.

CIPROX® (ciprofloxacin hydrochloride) Structural Formula Illustration
CIPROX film-coated tablets are available in 250 mg and 500 mg (ciprofloxacin equivalent) strengths. CIPROX tablets are white to slightly yellowish. The inactive ingredients are cornstarch, microcrystalline cellulose, silicon dioxide, crospovidone, magnesium stearate, hypromellose, titanium dioxide, and polyethylene glycol.
CIPROX Oral Suspension is available in 5% (5 g ciprofloxacin in 100 mL) and 10% (10 g ciprofloxacin in 100 mL) strengths. CIPROX Oral Suspension is a white to slightly yellowish suspension with strawberry flavor which may contain yellow-orange droplets. It is composed of ciprofloxacin microcapsules and diluent which are mixed prior to dispensing [see DOSAGE AND ADMINISTRATION].
Microcapsules–ciprofloxacin, povidone, methacrylic acid copolymer, hypromellose, magnesium stearate, and Polysorbate 20.

Diluent–medium-chain triglycerides, sucrose, soy-lecithin, water, and strawberry flavor.
Five (5) mL of 5% suspension contains approximately 1.4 g of sucrose and 5 mL of 10% suspension contains approximately 1.3 g of sucrose.

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